|
|
|
|
|
Isaak Y. Tecle; Naama Menda; Robert Buels; Lukas Mueller. |
Quantitative trait loci (QTL) analysis is used to dissect the genetic basis underlying polygenic traits. Several public databases have been storing and making QTL data available to research communities. To our knowledge, current QTL databases rely on manual curation where curators read literature and extract relevant QTL information to store in databases. Evidently, this approach is expensive in terms of expert manpower and time use and limits the type of data that can be curated. At the Solanaceae Genomics Network (SGN) ("http://sgn.cornell.edu":http://sgn.cornell.edu), we have developed a database to store raw phenotype and genotype data from QTL studies, perform, on the fly, QTL analysis using R/QTL statistical software... |
Tipo: Poster |
Palavras-chave: Genetics & Genomics; Bioinformatics; Plant Biology. |
Ano: 2009 |
URL: http://precedings.nature.com/documents/3160/version/1 |
| |
|
|
Anuradha Pujar; Ron Caspi; Naama Menda; Isaak Tecle; Peter Karp; Lukas Mueller. |
MetaCyc is a metabolic encyclopedia of experimentally validated biochemical pathways curated from scientific literature, that spans all organisms, with an emphasis on plants and microbes. The Pathway tools is a complex curation software suite that enables curation of reactions, construction of pathways and annotation with one or more representative enzymes, that include information such as substrate specificity, kinetic properties, activators, inhibitors, cofactor requirements, genes if cloned and links to external databases. In addition curators are able to provide concise, review-level summaries and extensive literature citations. The present database release includes more than 1200 pathways from more than 1549 organisms, 7312 reactions, 5127 enzymes,... |
Tipo: Poster |
Palavras-chave: Bioinformatics. |
Ano: 2009 |
URL: http://precedings.nature.com/documents/3192/version/1 |
| |
|
| |
|
|
|