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Mohansrinivasan,V.; Devi C.,Subathra; Deori,Meenakshi; Biswas,Ananya; Naine S,Jemimah. |
In this study, grape seeds were extracted using ethyl acetate and petroleum ether by solvent-solvent extraction method. The phytochemical tests were performed to identify different phytochemical compounds present in the grape seed extract (GSE). Antibacterial activity of the GSE was determined using agar diffusion method against Gram- positive and Gram-negative bacteria. Gas chromatography-mass spectrometry (GC-MS) and Fourier transform infrared spectroscopy (FTIR) analysis was done to identify the presence of bioactive compounds and their functional groups. The GC-MS results revealed a total of four compounds, known to have potent activity against cancer cells, viz, squalene, the most potent compound found in ethyl acetate extract and diethyl phthalate,... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: GSE (Grape seed extract); Phytochemical; FTIR; GCMS; Skin cancer cell line; Anticancer agents. |
Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132015000400540 |
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