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Effect of hyperglycemia on inflammatory markers in patients with Type 2 Diabetes Nature Precedings
Rajeev Goyal; Abul F. Faizy; Najmul Islam.
The role of inflammation in causation of both Diabetes and its complications has gained acceptance. Initially, hyperglycemia was thought to be the factor causing inflammation, but recently, obesity has gained attraction as probable cause of inflammation. We have studied the levels of markers of inflammation in Diabetic patients, with uncontrolled hyperglycemia, before and after treatment. The results indicate that hyperglycemia significantly causes increase in inflammatory markers like TNF-α and IL-6, which further contribute to pathogenesis of Diabetes mellitus type 2 as well as its complications such as atherosclerosis and neuropathy.
Tipo: Poster Palavras-chave: Immunology.
Ano: 2008 URL: http://precedings.nature.com/documents/1567/version/1
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Beneficial role of allicin from garlic in cervical cancer Nature Precedings
Irfan Ahmad Ansari; Najmul Islam.
Introduction: Cervical cancer remains a global health concern for females. Thus, in order to control cervical cancer, attempts are being made by researchers globally to somehow induce programmed cell death in the said cancerous cells. Wide spectrums of molecules are being probed for its ability to induce apoptosis in cervical cancer cells. Focus has now shifted in exploring natural compounds having antioxidant and anti-inflammatory molecules that may induce apoptosis in cancerous cells. Thus, we have employed allicin from garlic- a natural antioxidant, to probe the above in the present study.
Objective: To probe whether or not allicin from garlic, a natural antioxidant, induces apoptosis in monocytes from patients with cervical...
Tipo: Poster Palavras-chave: Cancer; Molecular Cell Biology.
Ano: 2008 URL: http://precedings.nature.com/documents/1561/version/1
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