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Molena-Fernandes,C.; Bersani-Amado,C. A.; Ferraro,Z. M.; Hintze,L. J.; Nardo Jr.,N.; Cuman,R. K. N.. |
We aimed to evaluate the effects of aerobic exercise training (4 days) and metformin exposure on acute glucose intolerance after dexamethasone treatment in rats. Forty-two adult male Wistar rats (8 weeks old) were divided randomly into four groups: sedentary control (SCT), sedentary dexamethasone-treated (SDX), training dexamethasone-treated (DPE), and dexamethasone and metformin treated group (DMT). Glucose tolerance tests and in situ liver perfusion were undertaken on fasting rats to obtain glucose profiles. The DPE group displayed a significant decrease in glucose values compared with the SDX group. Average glucose levels in the DPE group did not differ from those of the DMT group, so we suggest that exercise training corrects dexamethasone-induced... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Exercise; Glucose intolerance; Dexamethasone; Wistar rats; Diabetes mellitus; Prevention and control. |
Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2015001201101 |
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