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Guideline values and human risk assessment for the presence of anti-inflammatory drugs remaining in drinking water after lab scale treatment BJPS
Pais,Mariana Castello Novo; Nascimento,Elizabeth de Souza.
Abstract This study aimed to determine whether the anti-inflammatory drugs that are most commonly consumed in Brazil, including diclofenac, ketoprofen, naproxen, indomethacin, ibuprofen and acetaminophen, are present in drinking water and to derive guideline values to characterize the human risk. These pharmaceuticals were quantified in surface waters by LC-MS/MS with solid phase extraction, both before and after conventional treatment on a laboratory scale, using a jar test assay. The methods used to quantify these drugs showed good results: the chromatographic analysis obtained correlation coefficients between 0.9952 and 0.9991, with limits of quantification of 0.5 ng.mL-1 - 50 ng.mL-1 and precision standard deviations (0.08 - 2.08). Only ketoprofen and...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Emerging contaminant; LC-MS/MS; Human risk assessment; Pharmaceuticals in drinking water..
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502018000100624
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Chemical waste risk reduction and environmental impact generated by laboratory activities in research and teaching institutions BJPS
Nascimento,Elizabeth de Souza; Tenuta Filho,Alfredo.
The environmental impact caused by teaching and research with regard to chemical waste is of increasing concern, and attempts to solve the issue are being made. Education and research-related institutions, in most laboratory and non-laboratory activities, contribute to the generation of small quantities of waste, many of them highly toxic. Of this waste, some is listed by government agencies who are concerned about environmental pollution: disposal of acids, metals, solvents, chemicals and toxicity of selected products of synthesis, whose toxicity is often unknown. This article presents an assessment of the problem and identifies possible solutions, indicating pertinent laws, directives and guidelines; examples of institutions that have implemented...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Laboratory chemical waste/management in universities; Environmental safety; Environmental education.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502010000200004
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