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	Provedor de dados BJMBR (1) Autor Camara-Lopes,L.H. (1) Leite,K.R.M. (1) Nesralhah,L.J. (1) Srougi,M. (1) Palavra-chave P53 (1) PCNA (1) Proliferating cell nuclear antigen (1) Prostate carcinoma (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 1999 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Analysis of p53 expression and proliferative assessment using PCNA in localized prostate carcinoma BJMBR Leite,K.R.M.; Srougi,M.; Nesralhah,L.J.; Camara-Lopes,L.H.. The surgical specimens from 51 men submitted to radical prostatectomy for localized prostate cancer were examined by immunohistochemistry using proliferation cell nuclear antigen (PCNA) monoclonal antibody to evaluate the proliferative index (PI). The relationship between PI, biological variables and p53 protein expression was evaluated by immunohistochemistry. PI was low in invasive localized prostate carcinoma (mean, 12.4%) and the incidence of PCNA-positive cells was significantly higher in tumors with p53 expression (P = 0.0226). There was no statistical difference in PCNA values when biological parameters such as Gleason score, tumor volume, extraprostatic involvement, seminal vesicle infiltration or lymph node metastasis were considered. We conclude... Tipo: Info:eu-repo/semantics/article Palavras-chave: Prostate carcinoma; P53; Proliferating cell nuclear antigen; PCNA. Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000300006 Registros recuperados: 1 Primeira ... 1 ... Última

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