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Analysis of different levels of positive end-expiratory pressure during lung retrieval for transplantation: an experimental study BJMBR
Gonçalves-Ferri,W.A.; Jauregui,A.; Martins-Celini,F.P.; Sansano,I.; Fabro,A.T.; Sacramento,E.M.F.; Aragon,D.C.; Ochoa,J.M..
Atelectasis and inadequate oxygenation in lung donors is a common problem during the retrieval of these organs. Nevertheless, the use of high positive end-expiratory pressure (PEEP) is not habitual during procedures of lung retrieval. Twenty-one Sprague-Dawley male consanguineous rats were used in the study. The animals were divided into 3 groups according to the level of PEEP used: low (2 cmH2O), moderate (5 cmH2O), and high (10 cmH2O). Animals were ventilated with a tidal volume of 6 mL/kg. Before lung removal, the lungs were inspected for the presence of atelectasis. When atelectasis was detected, alveolar recruitment maneuvers were performed. Blood gasometric analysis was performed immediately. Finally, the lungs were retrieved, weighed, and submitted...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Anesthesia; Lung transplantation; Mechanical ventilation; Pulmonary recruitment; PEEP.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2019000700607
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