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	Provedor de dados BJMBR (1) Autor Chimeno Zoth,S. (1) Leunda,M.R. (1) Odeón,A. (1) Taboga,O. (1) Palavra-chave Bovine viral diarrhea virus (1) Recombinant E2 glycoprotein (1) Tipo do documento Info:eu-repo/semantics/other (1) Ano 2007 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Recombinant E2 glycoprotein of bovine viral diarrhea virus induces a solid humoral neutralizing immune response but fails to confer total protection in cattle BJMBR Chimeno Zoth,S.; Leunda,M.R.; Odeón,A.; Taboga,O.. Two recombinant baculoviruses were produced in order to obtain a bovine viral diarrhea virus (BVDV) immunogen: AcNPV/E2 expressing E2 glycoprotein, and AcNPV/E0E1E2 expressing the polyprotein region coding for the three structural proteins of BVDV (E0, E1, and E2). Mice were immunized with Sf9 cells infected with the recombinant baculoviruses in a water in oil formulation and the production of neutralizing antibodies was evaluated. Since E2 elicited higher neutralizing antibody titers than E0-E1-E2 polyprotein, it was selected to immunize cattle. Calves received two doses of recombinant E2 vaccine and were challenged with homologous BVDV 37 days later. The recombinant immunogen induced neutralizing titers which showed a mean value of 1.5 ± 0.27 on the day... Tipo: Info:eu-repo/semantics/other Palavras-chave: Bovine viral diarrhea virus; Recombinant E2 glycoprotein. Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000600010 Registros recuperados: 1 Primeira ... 1 ... Última

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