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Bui, Vuong N.; Nguyen, Khong V.; Pham, Nga T.; Bui, Anh N.; Dao, Tung D.; Nguyen, Thanh T.; Nguyen, Hoa T.; Trinh, Dai Q.; Inui, Kenjiro; Uchiumi, Hiroshi; Ogawa, Haruko; Imai, Kunitoshi. |
Acidic electrolyzed water (EW) (pH 2.6-5.8) and alkaline EW (pH 11.2-12.1) were examined as potential disinfectants against foot-and-mouth disease virus (FMDV). Using acidic EW with pH 2.6 and alkaline EW with pH > 11.7, the viral titer decreased in vitro by > 4.0 log values, 2 min after the virus was mixed with EW at a 1: 10 dilution. The strong virucidal effect of acidic EW (pH 2.6), but not that of alkaline EW (> 11.7), seemed to depend on the chlorine level in the solution. Genetic analysis revealed that viral RNA was substantially reduced, especially by alkaline EW. |
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Palavras-chave: Disinfectant; Electrolyzed water; Foot-and-mouth disease virus; Virucidal. |
Ano: 2017 |
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4516 |
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Sultan, Serageldeen; Vuong Nghia Bui; Hill, Nichola J.; Hussein, Islam T. M.; Dai Quang Trinh; Inage, Kumiko; Hashizume, Taishi; Runstadler, Jonathan A.; Ogawa, Haruko; Imai, Kunitoshi. |
Low-pathogenic avian influenza viruses (LPAIVs) of the H5 subtype can mutate to highly pathogenic forms, potentially destabilizing the poultry industry. Wild migratory birds are considered a natural reservoir of LPAIVs capable of dispersing both high- and low-pathogenic forms of the virus. Therefore, surveillance and characterization of AIV in wild birds are essential. Here, we report on the isolation and genetic characterization of 10 AIVs of the H5N2 subtype obtained through surveillance in Hokkaido, Japan, during 2009 and 2011. Full-genome sequencing revealed that the H5 and N2 genes of these isolates are all closely related to each other, belonging to the Eurasian avian-like lineage, but they are unrelated to H5 highly pathogenic strains of clade... |
Ano: 2016 |
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4568 |
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