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| Okur,Mehmet Evren; Özbek,Hanefi; Polat,Derya Çiçek; Yılmaz,Sezen; Arslan,Rana. |
| Caper (Capparis ovata Desf. and Capparis spinosa L.) is naturally widespread in Turkey. Traditionally, buds, fruits, seeds and roots of this plant are used as tonic, diuretic, anti-rheumatic, expectorant, antidiabetic, and antifungal. The aim of this study is to evaluate potential hypoglycemic effect of C. ovata var. palaestina extracts in alloxan-induced diabetic mice. For this purpose; diabetic mice were administered with 100, 300, 500 mg/kg (i.p.) doses of methanol extract of bud and fruit. Blood glucose levels were screened 60, 120, 240 and 360 min. after treatment. Furthermore, high resolution mass spectrometry (HRMS) analysis, ABTS and DPPH free radical scavenging activity test, and phenolic and flavonoid compounds analysis of extracts were carried... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: C. ovata var. palaestina/extract; C. ovata var; Palaestina/hypoglycemic effect/antioxidant effects; Diabetes mellitus; Mice. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502018000300630 |
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| Siafaka,Panoraia; Okur,Mehmet Evren; Ayla,Şule; Er,Sevda; Cağlar,Emre Şefik; Okur,Neslihan Üstündağ. |
| Inorganic and carbon based nanomaterials are widely used against several diseases, such as cancer, autoimmune diseases as well as fungi and bacteria colonization. In this work, Santa Barbara Amorphous mesoporous silica (SBA), Halloysite Nanotubes (HNTs) and Multiwalled Carbon Nanotubes (CNTs) were loaded with fluoroquinolone Levofloxacin (LVF) to be applied as antimicrobial agents. The prepared via adsorption nanocarriers were characterized by Fourier-Transformed Spectroscopy, Scanning Electron Microscopy as well as High Pressure liquid Chromatography. In vitro release studies were carried out using Simulated Body Fluid at 37oC and data analyzed by various kinetic models showing slow dissolution over 12-24 hours. Antimicrobial studies showed improved... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Carbon nanotubes; Santa barbara amorphous; Halloysite nanotubes; Levofloxacin; Toxicity; Antimicrobial. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100514 |
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