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	Provedor de dados BJMBR (2) Autor Oliveira,E.B. (2) Antas,P.R.Z. (1) Becari,C. (1) Cunha,K.S. (1) Pereira,K.C. (1) Sales,J.S. (1) Salgado,M.C.O. (1) Sampaio,E.P. (1) Sarno,E.N. (1) Mais... Palavra-chave Alternative pathway (1) Angiotensin II (1) Angiotensin-converting enzyme (1) Anti-hCD28 mAb (1) IFN-gamma (1) Leprosy (1) Rat elastase-2 (1) Renin-angiotensin system (1) TNF-alpha (1) Tuberculosis (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2011 (1) 2004 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Alternative pathways for angiotensin II generation in the cardiovascular system BJMBR Becari,C.; Oliveira,E.B.; Salgado,M.C.O.. The classical renin-angiotensin system (RAS) consists of enzymes and peptides that regulate blood pressure and electrolyte and fluid homeostasis. Angiotensin II (Ang II) is one of the most important and extensively studied components of the RAS. The beneficial effects of angiotensin converting enzyme (ACE) inhibitors in the treatment of hypertension and heart failure, among other diseases, are well known. However, it has been reported that patients chronically treated with effective doses of these inhibitors do not show suppression of Ang II formation, suggesting the involvement of pathways alternative to ACE in the generation of Ang II. Moreover, the finding that the concentration of Ang II is preserved in the kidney, heart and lungs of mice with an ACE... Tipo: Info:eu-repo/semantics/article Palavras-chave: Renin-angiotensin system; Angiotensin II; Rat elastase-2; Alternative pathway; Angiotensin-converting enzyme. Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011000900013 Patterns of intracellular cytokines in CD4 and CD8 T cells from patients with mycobacterial infections BJMBR Antas,P.R.Z.; Sales,J.S.; Pereira,K.C.; Oliveira,E.B.; Cunha,K.S.; Sarno,E.N.; Sampaio,E.P.. Using a short-term bulk culture protocol designed for an intracellular-staining method based on a flow cytometry approach to the frequencies of cytokine-producing cells from tuberculosis and leprosy patients, we found distinct patterns of T cell subset expression. The method also reveals the profile of peak cytokine production and can provide simultaneous information about the phenotype of cytokine-producing cells, providing a reliable assay for monitoring the immunity of these patients. The immune response of Mycobacterium leprae and purified protein derivative (PPD) in vitro to a panel of mycobacteria-infected patients from an endemic area was assessed in primary mononuclear cell cultures. The kinetics and source of the cytokine pattern were measured at... Tipo: Info:eu-repo/semantics/article Palavras-chave: Tuberculosis; Leprosy; IFN-gamma; TNF-alpha; Anti-hCD28 mAb. Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000800003 Registros recuperados: 2 Primeira ... 1 ... Última

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