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Barros,Séfora Vieira da Silva Gouvêa de; Aldrovani,Marcela; Lacerda,Luciana Cenço Correa de; Horr,Mônica; Marinho,Fábio Andrade; Lima,Tiago Barbalho; Silveira,Camila Pinho Balthazar da; Brito,Fábio Luiz da Cunha; Bassaneze,Vinícius; Flecher,Mayra Cunha; Beltrame,Renato Travassos; Nakamuta,Juliana Sanajotti; Krieger,José Eduardo; Laus,José Luiz; Oliveira,Krishna Duro de. |
ABSTRACT: The objective of this research was to evaluate the clinical and microscopic effects in rabbits of lamellar keratoplasty using allogeneic omentum associated with canine amniotic membrane (AM). Rabbits were divided into two groups: one received the allogeneic free omental graft covered with the AM (OM-graft group), while the other received the AM graft containing omental mesenchymal cells (OM-cell group). Clinical signs were evaluated on different postoperative days. After the clinical assessments, the rabbits were euthanized and their corneas were obtained for histopathology and immunohistochemistry (Ki-67, marker for proliferation). Both groups showed chemosis, blepharospasm, eye discharge, hyperemia, and corneal opacity/edema. Neovascularization... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Amniotic membrane; Cornea; Omentum; Progenitor cells; Wound healing.. |
Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782016001001838 |
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