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| Delgobo,Murilo; Paludo,Katia Sabrina; Fernandes,Daniel; Oliveira,Junior Garcia de; Ortolan,Gilberto Luiz; Favero,Giovani Marino. |
| Abstract The gut is the main organ that mediates the contact between antigens with our organism, controlling the immune response against environmental factors, such as microbiota and food. Innate lymphoid cells participate in the gut-associated lymphoid tissue (GALT) maturation during the prenatal and early postnatal periods. After birth, breast milk provides the essential elements for the continuity of development of this tissue, leading to structural changes and healthy microbiota installation. The microbiota participates in the organogenesis of the GALT, as in the formation of intestinal villi, stimulating the proliferation of stem cells and maintaining the integrity of epithelial barrier. Foods are also involved in maturation of the GALT, where the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Immunology; Gut; Peripheral Tolerance. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132019000100901 |
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