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Diet high in α-linolenic acid up-regulate PPAR-α gene expression in the liver of goats Electron. J. Biotechnol.
Ebrahimi,Mahdi; Rajion,Mohamed Ali; Meng,Goh Yong; Farjam,Abdoreza Soleimani; Oskoueian,Ehsan; Jafari,Saeid.
Background There is little information on the effects of diets containing high &#945;-linolenic acid (C18:3n-3) on liver lipid composition and lipogenic gene expressions. In this study fourteen goats (Capra aegagrus hircus) were fed either a flaxseed oil (FSO) supplemented diet containing high &#945;-linolenic acid or a control diet without added flaxseed oil (CON) for 100-d to evaluate the effects on liver lipid composition and the gene expression of peroxisome proliferator-activated receptors (PPAR-&#945;) and stearoyl-CoA-desaturase (SCD) in the liver. Results An increase in the levels of C18:3n-3 and C20:5n-3, C22:5n-3, C22:6n-3 was observed in the liver of FSO-treated goats. There was a significant (P < 0.05) up-regulation of...
Tipo: Journal article Palavras-chave: Gene expression; Goat; Liver; Omega-3 fatty acid; PPAR.
Ano: 2015 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582015000300011
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