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	Provedor de dados BJID (1) Autor Castañón-Sánchez,Carlos A. (1) Marchat,Laurence A. (1) Ospina-Villa,Juan David (1) Ramírez-Moreno,Esther (1) Zamorano-Carrillo,Absalom (1) Palavra-chave Aptamer (1) Parasite control (1) Protozoan parasite (1) SELEX strategy (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2016 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Aptamers as a promising approach for the control of parasitic diseases BJID Ospina-Villa,Juan David; Zamorano-Carrillo,Absalom; Castañón-Sánchez,Carlos A.; Ramírez-Moreno,Esther; Marchat,Laurence A.. ABSTRACT Aptamers are short single-stranded RNA or DNA oligonucleotides that are capable of binding various biological targets with high affinity and specificity. Their identification initially relies on a molecular process named SELEX (Systematic Evolution of Ligands by EXponential enrichment) that has been later modified in order to improve aptamer sensitivity, minimize duration and cost of the assay, as well as increase target types. Several biochemical modifications can help to enhance aptamer stability without affecting significantly target interaction. As a result, aptamers have generated a large interest as promising tools to compete with monoclonal antibodies for detection and inhibition of specific markers of human diseases. One aptamer-based drug... Tipo: Info:eu-repo/semantics/article Palavras-chave: Aptamer; Parasite control; Protozoan parasite; SELEX strategy. Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702016000600610 Registros recuperados: 1 Primeira ... 1 ... Última

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