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| NOGUEIRA,DENISE M.; ARMADA,JORGE L.A.; PENEDO,DIEGO M.; TANNOUZ,VANIA G.S.; MEYERS-WALLEN,VICKI N.. |
| Abstract: Here we describe an eight-year-old miniature schnauzer (MS) dog from Brazil with Persistent Mullerian Duct Syndrome (PMDS) and the single base pair substitution in AMHR2 exon 3, first detected in this breed in the USA. This finding is evidence of mutation dissemination to South America. In PMDS, a type of XY Disorder of Sex Development (DSD), dogs with a male karyotype and external phenotype also have a uterus, oviducts, and a cranial vagina internally. Approximately half of PMDS MS are unilaterally or bilaterally cryptorchid and many develop pyometra and/or Sertoli cell tumor. Bilateral Sertoli cell testicular tumors were present in this case, and the dog died a few days after surgical castration and hysterectomy. Although the karyotype was... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: 78; XY Disorders of Sex Development; AMHR2 exon 3 mutation; Canine; PMDS. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000300712 |
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