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Ultrastructural effects of two phthalocyanines in CHO-K1 and HeLa cells after laser irradiation Biocell
de CastroPazos,Marcelo; Pacheco-Soares,Cristina; Soares da Silva,Newton; DaMatta,Renato Augusto; Pacheco,Marcos Tadeu T..
The effects of Photodynamic Therapy using 2nd generation photosensitizers have been widely investigated aiming clinical application treatment of solid neoplasms. In this work, ultrastructure changes caused by the action of two 2nd generation photosensitizers and laser irradiation on CHO-K1 and HeLa (neoplastic) cells were analyzed by transmission electron microscopy. Aluminum phthalocyanine chloride, aluminum phthalocyanine tetrasulfonate chloride and radiation from a semiconductor laser at a fluency of 0.5 J/cm² (Power=26mW; l=670nm) were used. The results showed induction of apoptosis. Such alterations where observed in HeLa but not in CHO-K1 cells after Aluminum phthalocyanine tetrasulfonate chloride (AlPcS4) photodynamic treatment. The Aluminum...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Photodynamic therapy; Phthalocyanines; Laser; Cell death; Ultrastructure.
Ano: 2003 URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0327-95452003000300001
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Effects of the infrared lamp illumination during the process of muscle fatigue in rats BABT
Abou-Hala,Andréia Zarzour; Barbosa,Daniella Galvão; Marcos,Rodrigo Labat; Pacheco-Soares,Cristina; Silva,Newton Soares da.
In this study the effects of infrared lamp illumination during the muscle fatigue process was studied. Three different groups (n=5) were used: one control group and two treated (Infrared Lamp 780-1400nm), with the energy densities of 0.5 and 1.0 J/cm² and time of illumination of 300 seconds. The treated animals were illuminated in one point directly in the tibialis muscle, after the first tetanic contraction out of six, with an interval between each tetany. The results were registered in an electrophysiograph and the intensity of the force of contraction in grams was analysed. It was observed that the control group presented a reduction in the intensity of the force of contraction, while the treated group managed to maintain it, which was clearly evident...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Muscle fatigue; Infrared illumination; Muscle tension; Tetany.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132007000300006
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