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Incorporation of dietary trans monounsaturated fatty acids into tissues of Walker 256 tumor-bearing rats BJMBR
Moreira,N.X.; Curi,R.; Padovese,R.; Mancini-Filho,J..
The correlation between dietary trans fatty acids and neoplasia was examined in the present study. Walker 256 tumor-bearing and control rats were fed a trans monounsaturated fatty acid (MUFA)-rich diet for 8 weeks and the incorporation of trans fatty acids by tumor tissue was examined. Also, the effect of tumor growth on trans fatty acid composition of plasma and liver, and the content of thiobarbituric acid-reactive substances (TBARS) was determined. Walker 256 tumor cells presented both trans and cis MUFAs given in the diet. The equivalent diet proportions were 0.66 for trans and 1.14 for cis. Taking into consideration the proportion of trans MUFAs in plasma (11.47%), the tumor incorporated these fatty acids in a more efficient manner (18.27%) than the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Trans fatty acids; Walker 256 tumor; Fatty acid composition; Lipid peroxidation.
Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000400010
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