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| Oliveira Filho,R.S.; Ferreira,L.M.; Biasi,L.J.; Enokihara,M.M.S.S.; Paiva,G.R.; Wagner,J.. |
| Sentinel node (SN) status is the most important prognostic factor for localized melanoma. Usually, patients with Breslow thickness of less than 1.0 mm are not included in SN protocols. However, the literature presents a rate ranging from 3 to 7% of nodal recurrence in thin melanoma. Ulceration, regression and high mitotic rate have been considered to be indications for an SN biopsy. The metastatic potential of the vertical growth phase is uncertain. To correlate pathological features in thin melanoma with SN metastasis, we reviewed 358 patients submitted to SN biopsy. Seventy-seven patients with lesions of 1 mm or smaller were included in the study group. Histological evaluation of the primary tumor included thickness, Clark level, mitotic rate,... |
| Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Thin melanoma; Sentinel node; Lymphoscintigraphy; Immunohistochemistry; Micrometastasis. |
| Ano: 2003 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000300009 |
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