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	Provedor de dados BJPS (1) Autor Pandit,Ashlesha Pravin (1) Shinde,Rajendra Dattatray (1) Palavra-chave Coating (1) Cushning agent (1) HPMC E15 (1) Metoprolol succinate (1) Nonpareil seeds (1) Pellets (1) Solution layering technique (1) Surelease® (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Ano 2010 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Development and in vitro evaluation of sustained release multiparticulate tablet of freely water soluble drug BJPS Pandit,Ashlesha Pravin; Shinde,Rajendra Dattatray. Blends of aqueous dispersion of a hydrophobic and hydrophilic polymer, namely Surelease®: hydroxypropyl methylcellulose (Surelease®: HPMC E15) were used as coating materials to control the drug release from coated pellets of the highly water soluble drug metoprolol succinate. Varying the polymer blends, ranges of drug release patterns were obtained at pH 6.8. The present study dealt with diffusion of drug through plasticized Surelease®/ hydroxypropyl methylcellulose (HPMC E15) films prepared by coating of drug and polymers onto non-pareil seeds using the solution layering technique. The release of metoprolol succinate from coated pellets was decreased with increased coating load of polymer. The optimized formulation was obtained by 3² full factorial... Tipo: Info:eu-repo/semantics/article Palavras-chave: Pellets; Nonpareil seeds; Surelease®; HPMC E15; Coating; Solution layering technique; Cushning agent; Metoprolol succinate. Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502010000300009 Registros recuperados: 1 Primeira ... 1 ... Última

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