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Anti-hepatitis C virus treatment may prevent the progression of liver fibrosis in non-responder human immunodeficiency virus/hepatitis C virus coinfected patients BJID
Sagnelli,Caterina; Uberti-Foppa,Caterina; Galli,Laura; Pasquale,Giuseppe; Coppola,Nicola; Albarello,Luca; Doglioni,Carlo; Lazzarin,Adriano; Sagnelli,Evangelista.
AIM:To evaluate changes in liver histology in patients with human immunodeficiency virus/hepatitis C virus coinfection non-responders to a suboptimal Interferon+Ribavirine regimen.MATERIALS AND METHODS:We investigated 49 patients with two sequential liver biopsies: 18 were non-responders to Interferon+Ribavirine treatment (Group hepatitis C virus Rx) administered after the 1st liver biopsy who underwent a 2nd liver biopsy after a median period of 3.92 year and 31 were patients who remained untreated for hepatitis C virus disease (Group hepatitis C virus untreated) after the 1st liver biopsy because of refusal and underwent a 2nd liver biopsy after a median period of 5.05-years. Most patients in both groups were under highly active antiretroviral therapy....
Tipo: Info:eu-repo/semantics/article Palavras-chave: HIV/HCV coinfection; HIV infection; HIV/HCV coinfection liver histology; Liver fibrosis.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000200164
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