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Protein carbonyl content: a novel biomarker for aging in HIV/AIDS patients BJID
Kolgiri,Vaishali; Patil,Vinayak Wamanrao.
Abstract Background: The major complications of “treated” Human Immunodeficiency Virus (HIV) infection are cardiovascular disease, malignancy, renal disease, liver disease, bone disease, and perhaps neurological complications, which are phenomena of the normal aging process occurring at an earlier age in the HIV-infected population. The present study is aimed to explore protein carbonyl content as a biomarker for detecting oxidative DNA damage induced ART toxicity and/or accelerated aging in HIV/AIDS patients. Objective: To investigate the potential of carbonyl content as a biomarker for detecting oxidative Deoxyribonucleic acid (DNA) damage induced Antiretroviral Theraphy (ART) toxicity and/or accelerated aging in HIV/AIDS patients. Methods: In this...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Carbonyl content; DNA damage; Human immunodeficiency virus (HIV) infection; 8-OH-dG; ROS.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702017000100035
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