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	Provedor de dados BJID (3) Autor Pavan,Maria Helena Postal (3) Gonçales Jr,Fernando Lopes (2) Escanhoela,Cecília Amélia Fazio (1) Fais,Viviane (1) Feltrin,Adriana (1) Genari,Flavia (1) Gonçales Junior,Fernando Lopes (1) Gonçales,Eduardo Sellan (1) Gonçales,Neiva Sellan (1) Gonçales,Neiva Sellan Lopes (1) Lazarini,Maria Silvia Kroll (1) Pavin,Elizabeth João (1) Pereira,Josiane Silveira Felix (1) Silva,Claudia da (1) Tozzo,Raquel (1) Vigani,Aline Gonzalez (1) Zantut-Wittmann,Denise Engelbrecht (1) Mais... Palavra-chave Chronic interferon-α (1) HCV genotype interferon treatment (1) Hepatitis C (1) Hypothyroidism hepatitis C (1) Interferons (1) Occult HBV infection chronic HCV infection HBV-DNA PCR (1) Treatment outcome (1) Mais... Tipo do documento Info:eu-repo/semantics/article (3) Ano 2012 (1) 2011 (1) 2004 (1) País Brazil (3) Idioma Inglês (3)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 3 Primeira ... 1 ... Última Therapeutic effectiveness of biosimilar standard interferon versus pegylated interferon for chronic hepatitis C genotypes 2 or 3 BJID Vigani,Aline Gonzalez; Gonçales,Eduardo Sellan; Pavan,Maria Helena Postal; Genari,Flavia; Tozzo,Raquel; Lazarini,Maria Silvia Kroll; Fais,Viviane; Feltrin,Adriana; Gonçales,Neiva Sellan; Gonçales Jr,Fernando Lopes. BACKGROUND: Pegylated interferon (Peg-IFN) and standard interferon (IFN) play a significant role in the treatment of hepatitis C virus (HCV) infection. Biosimilar standard IFN is widely available in Brazil for the treatment of HCV infection genotypes 2 or 3, but its efficacy compared to Peg-IFN is unknown. OBJECTIVE: To compare the sustained virological response (SVR) rates following treatment with biosimilar standard IFN plus ribavirin (RBV) versus Peg-IFN plus RBV in patients with HCV genotypes 2 or 3 infection. METHODS: A retrospective cohort study was conducted in patients with HCV genotypes 2 or 3 infection treated with biosimilar standard IFN plus RBV or with Peg-IFN plus RBV. SVR rates of the two treatments were compared. RESULTS: From January 2005... Tipo: Info:eu-repo/semantics/article Palavras-chave: Interferons; Hepatitis C; Treatment outcome. Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000300003 Virus C genotype predisposes to primary hypothyroidism during interferon-α treatment for chronic hepatitis C BJID Pavan,Maria Helena Postal; Pavin,Elizabeth João; Gonçales Jr,Fernando Lopes; Zantut-Wittmann,Denise Engelbrecht. OBJECTIVE: The treatment of the chronic hepatitis C (HCV) with α-interferon is associated with thyroid dysfunction (TD). The aim of this study was to evaluate thyroid function outcome among patients with chronic HCV under treatment with conventional interferon (IFN) or peguilated interferon (PEG-IFN) in association with ribavirin. PATIENTS AND METHODS: We studied 293 patients with chronic HCV, submitted to drug therapy for 24 or 48 weeks. Initially, we evaluated FT4, TSH, TPOAb, TgAb, and continued to monitor FT4 and TSH every three months during therapy and six months thereafter. RESULTS: At baseline, TD prevalence was 6.82% (n = 20); 6.14% hypothyroidism; 0.68% hyperthyroidism. TPOAb was present in 5.46% of euthyroid patients. Out of 273 euthyroid... Tipo: Info:eu-repo/semantics/article Palavras-chave: Hypothyroidism hepatitis C; Chronic interferon-α. Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000500006 The influence of occult infection with hepatitis B virus on liver histology and response to interferon treatment in chronic hepatitis C patients BJID Silva,Claudia da; Gonçales,Neiva Sellan Lopes; Pereira,Josiane Silveira Felix; Escanhoela,Cecília Amélia Fazio; Pavan,Maria Helena Postal; Gonçales Junior,Fernando Lopes. Occult hepatitis B virus (HBV) infections have been identified in patients with chronic hepatitis C virus (HCV) infection, although the clinical relevance of occult HBV infection remains controversial. We searched for serum HBV DNA in 106 HBsAg negative/anti-HBc positive patients with chronic HCV infection and in 150 blood donors HBsAg negative/anti-HBc positive/anti-HCV negative (control group) by nested-PCR. HCV genotyping was done in 98 patients and percutaneous needle liver biopsies were performed in 59 patients. Fifty-two patients were treated for HCV infection with interferon alone (n=4) or combined with ribavirin (n=48) during one year. At the end and 24 weeks after stopping therapy, they were tested for HCV-RNA to evaluate the sustained virological... Tipo: Info:eu-repo/semantics/article Palavras-chave: Occult HBV infection chronic HCV infection HBV-DNA PCR; HCV genotype interferon treatment. Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702004000600007 Registros recuperados: 3 Primeira ... 1 ... Última

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