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Morphological and functional alterations of the intestine of rats with iron-deficiency anemia BJMBR
Wayhs,M.L.C.; Patrício,F.S.R.; Amancio,O.M.S.; Pedroso,M.Z.; Fagundes Neto,U.; Morais,M.B..
The present study was designed to assess the intestinal absorption of D-xylose and jejunal morphometry in rats with iron-deficiency anemia. Male Wistar rats were randomly divided into a control group (diet containing 50 mg Fe/kg, N = 12) and an anemic group (diet containing <5 mg Fe/kg, N = 12). The animals were housed in individual metabolic cages and deionized water and diet were provided ad libitum for 6 weeks. Hemoglobin and hematocrit were determined at 0, 2, 4, and 6 weeks. At the end of the study the rats were submitted to a D-xylose absorption test (50 mg/100 g body weight) and sacrificed and a jejunal specimen was obtained for morphometric study. At the end of the study the hemoglobin and hematocrit of the anemic rats (8.7 ± 0.9 g/dl and 34.1 ±...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Iron deficiency; Anemia; Jejunal villus height; Jejunal mucosal thickness; Jejunal epithelial surface.
Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004001100006
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Studies of the small bowel surface by scanning electron microscopy in infants with persistent diarrhea BJMBR
Fagundes-Neto,U.; De Martini-Costa,S.; Pedroso,M.Z.; Scaletsky,I.C.A..
We describe the ultrastructural abnormalities of the small bowel surface in 16 infants with persistent diarrhea. The age range of the patients was 2 to 10 months, mean 4.8 months. All patients had diarrhea lasting 14 or more days. Bacterial overgrowth of the colonic microflora in the jejunal secretion, at concentrations above 10(4) colonies/ml, was present in 11 (68.7%) patients. The stool culture was positive for an enteropathogenic agent in 8 (50.0%) patients: for EPEC O111 in 2, EPEC O119 in 1, EAEC in 1, and Shigella flexneri in 1; mixed infections due to EPEC O111 and EAEC in 1 patient, EPEC O119 and EAEC in 1 and EPEC O55, EPEC O111, EAEC and Shigella sonnei in 1. Morphological abnormalities in the small bowel mucosa were observed in all 16 patients,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Persistent diarrhea; Small bowel; Scanning electron microscopy; Bacterial proliferation; Infants.
Ano: 2000 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000001200006
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