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Azole resistance in Candida spp. isolated from Catú Lake, Ceará, Brazil: an efflux-pump-mediated mechanism BJM
Brilhante,Raimunda S.N.; Paiva,Manoel A.N.; Sampaio,Célia M.S.; Castelo-Branco,Débora S.C.M.; Teixeira,Carlos E.C.; Alencar,Lucas P. de; Bandeira,Tereza J.P.G.; Monteiro,André J.; Cordeiro,Rossana A.; Pereira-Neto,Waldemiro A.; Sidrim,José J.C.; Moreira,José L.B.; Rocha,Marcos F.G..
Abstract Since, there is no study reporting the mechanism of azole resistance among yeasts isolated from aquatic environments; the present study aims to investigate the occurrence of antifungal resistance among yeasts isolated from an aquatic environment, and assess the efflux-pump activity of the azole-resistant strains to better understand the mechanism of resistance for this group of drugs. For this purpose, monthly water and sediment samples were collected from Catú Lake, Ceará, Brazil, from March 2011 to February 2012. The obtained yeasts were identified based on morphological and biochemical characteristics. Of the 46 isolates, 37 were Candida spp., 4 were Trichosporon asahii, 3 were Cryptococcus laurentii, 1 Rhodotorula mucilaginosa, and 1 was...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Aquatic environments; Yeast microbiota; Candida spp.; Antifungal resistance.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822016000100033
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