Home Itens selecionados Provedores de dados OAI Créditos Sobre Ajuda

			Busca avançada
	Provedor de dados BJPS (3) Autor Pippi,Bruna (3) Fuentefria,Alexandre Meneghello (2) Balbueno,Eduardo A. (1) Bergamo,Vanessa Z. (1) Carvalho,Anderson Ramos (1) Fuentefria,Alexandre M. (1) Hatwig,Camila (1) Kaiser,Samuel (1) Lana,Aline Jacobi Dalla (1) Mezzari,Adelina (1) Moraes,Renata Cougo (1) Ortega,George Gonzalez (1) Rocha,Letícia Fernandes da (1) Silveira,Gustavo P. (1) Silveira,Gustavo Pozza (1) Mais... Palavra-chave Fluconazole (2) Anidulafungin (1) Biofilm (1) Candida glabrata (1) Cross-resistance (1) Cryptococcus neoformans (1) Dermatophyte (1) Drug combination. (1) Griseofulvin (1) Ibuprofen (1) Itraconazole (1) Multidrug-resistant fungi (1) Synergism (1) Terbinafine (1) Mais... Tipo do documento Info:eu-repo/semantics/article (3) Ano 2020 (1) 2019 (1) 2018 (1) País Brazil (3) Idioma Inglês (3)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 3 Primeira ... 1 ... Última In Vitro additive effect on griseofulvin and terbinafine combinations against multidrug-resistant dermatophytes BJPS Lana,Aline Jacobi Dalla; Pippi,Bruna; Carvalho,Anderson Ramos; Moraes,Renata Cougo; Kaiser,Samuel; Ortega,George Gonzalez; Fuentefria,Alexandre Meneghello; Silveira,Gustavo Pozza. ABSTRACT Griseofulvin (GF) and terbinafine (TF) are commonly used drugs to treat dermatophytosis, a fungal infection of the skin. Today there is an increase in drug resistance to these antifungals which highlight the need for alternative synergistic therapies. Minimum Inhibitory Concentration (MIC) of GF and TF were determined against fungi clinical isolates from local hospitals with values ranging 0.03-2.0 µg mL-1 and 0.24-4.0 µg mL-1, respectively. A checkboard test was used to determine the combination of GF:TF which could induce an additive effect against the fungi isolates Multidrug-resistant isolates showed susceptibility after treatment with 16:2 µg mL-1 GF:TF. An MTT assay further verified that GF and TF combinations have greater additive effect... Tipo: Info:eu-repo/semantics/article Palavras-chave: Griseofulvin; Terbinafine; Dermatophyte; Multidrug-resistant fungi; Drug combination.. Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502018000200623 Multidrug-resistant Candida glabrata strains obtained by induction of anidulafungin resistance in planktonic and biofilm cells BJPS Hatwig,Camila; Balbueno,Eduardo A.; Bergamo,Vanessa Z.; Pippi,Bruna; Fuentefria,Alexandre M.; Silveira,Gustavo P.. Candida glabrata has emerged as a common cause of serious life-threatening fungal infections, largely owing to their low susceptibility to azole antifungals. Recent guidance indicates the use of echinocandins as the first-choice drug for the treatment of systemic infections of C. glabrata; however, C. glabrata resistance to echinocandins is reportedly increasing. Herein, we present the induction of anidulafungin resistance in planktonic and sessile cells of C. glabrata and the development of fluconazole cross-resistance. MICs of 21 clinical C. glabrata strains were determined by a broth microdilution method using anidulafungin and fluconazole. Biofilm formation on a tracheal catheter was determined using 1- × 1-cm2 polyvinyl polychloride catheter... Tipo: Info:eu-repo/semantics/article Palavras-chave: Candida glabrata; Biofilm; Anidulafungin; Cross-resistance; Fluconazole. Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100604 Synergistic effect of ibuprofen with itraconazole and fluconazole against Cryptococcus neoformans BJPS Rocha,Letícia Fernandes da; Pippi,Bruna; Fuentefria,Alexandre Meneghello; Mezzari,Adelina. The present study investigated the association of the non-steroidal anti-inflammatory drug ibuprofen with itraconazole, fluconazole and amphotericin B against Cryptococcus neoformans isolates. The minimal inhibitory concentration (MIC) was found according to M27-A3 protocol and in vitro interactions were evaluated using checkerboard microdilution method. Synergism was demonstrated between azoles and ibuprofen for most isolates. However, no synergistic effects were seen when amphotericin B was combined with ibuprofen. Therefore, our results suggest that ibuprofen presents clinical potential when combined with azole drugs in the treatment of cryptococcosis. Tipo: Info:eu-repo/semantics/article Palavras-chave: Cryptococcus neoformans; Ibuprofen; Itraconazole; Fluconazole; Synergism. Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100577 Registros recuperados: 3 Primeira ... 1 ... Última

Empresa Brasileira de Pesquisa Agropecuária - Embrapa Todos os direitos reservados, conforme Lei n° 9.610 Política de Privacidade Área restrita		Embrapa Parque Estação Biológica - PqEB s/n° Brasília, DF - Brasil - CEP 70770-901 Fone: (61) 3448-4433 - Fax: (61) 3448-4890 / 3448-4891 SAC: https://www.embrapa.br/fale-conosco