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	Provedor de dados BABT (1) Autor Pujatti,Priscilla Brunelli (1) Santos,Raquel Gouvêa dos (1) Simal,Carlos Jorge Rodrigues (1) Palavra-chave Hemolytic activity (1) Labeling (1) Technetium-99m (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2005 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Preparation of crotalus venom radiolabeled with technetium-99m as a tool for biodistribution study BABT Pujatti,Priscilla Brunelli; Simal,Carlos Jorge Rodrigues; Santos,Raquel Gouvêa dos. Technetium-99m (99mTc) has been the radionuclide of choice for nuclear medicine procedures and experimental research. Because of its optimal nuclear properties, 99mTc is suitable for high efficiency detection with the advantage of reduced radiological waste. Crotalus venom (CV) has been shown to reduce tumors in clinical studies and tissue distribution studies are very important for clinical use. The goal of this work was to obtain CV labeled with 99mTc which preserves its biological activity. After labeling, biological activity was assessed by hemolytic activity evaluation. Labeled and crude venom caused indirect hemolysis provided that the incubation medium contained an exogenous source of lecithin. High yield radiolabeled-CV was obtained and biological... Tipo: Info:eu-repo/semantics/article Palavras-chave: Technetium-99m; Labeling; Hemolytic activity. Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132005000700002 Registros recuperados: 1 Primeira ... 1 ... Última

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