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Dexamethasone Regulates Macrophage and Cd4+Cd25+ Cell Numbers in the Chicken Spleen Rev. Bras. Ciênc. Avic.
Calefi,AS; Quinteiro-Filho,WM; Fukushima,AR; Cruz,DSG da; Siqueira,A de; Salvagni,FA; Namazu,LB; Gomes,COMS; Ferreira,AJP; Palermo Neto,J.
Abstract Dexamethasone (DEX) is a corticoid hormone that is experimentally used to mimic the effects of increased levels of endogenous corticosterone observed during the stress response. Currently, stress is considered one of the major predisposing factors for diseases in the poultry industry. The aim of this study was to analyze the effects of DEX and/or of a 20-fold coccidial vaccine dose on leukocyte phenotypes in the spleen and cecal tonsils of chickens. Twenty specific-pathogen-free (SPF) Leghorn chickens were divided into four groups: a non-treated group (NT), a DEX-treated group (Dex), a vaccinated group (V) and a DEX-treated+vaccinated group (Dex+V). On experimental day (ED) 42, each bird in the vaccinated groups received a anti-coccidial vaccine....
Tipo: Info:eu-repo/semantics/article Palavras-chave: Coccidiosis; Eimeria; Avian immunology; Flow cytometry; Neuroimmunomodulation.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-635X2016000100093
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