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	Provedor de dados Nature Precedings (2) Autor Ranjit Singh (2) Vikas Jain (2) Palavra-chave Chemistry (2) Pharmacology (2) Tipo do documento Manuscript (2) Ano 2009 (2) País United Kingdom (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Development and Characterization of Eudragit RS 100 Loaded Microsponges and its Colonic Delivery Using Natural Polysaccharides Nature Precedings Vikas Jain; Ranjit Singh. In the present work, paracetamol loaded eudragit based microsponges were prepared using quasi-emulsion solvent diffusion method. The compatibility of the drug with various formulation components was established. Process parameters were analyzed in order to optimize the formulation. Shape and surface morphology of the microsponges were examined using scanning electron microscopy. The colon specific formulations were prepared by compression coating of microsponges with pectin:hydroxypropylmethylcellulose (HPMC) mixture followed by tabletting. The in vitro dissolution studies were done on all formulations and the results were evaluated kinetically and statically. The kinetics of release study showed that the release data followed Higuchi matrix and the main... Tipo: Manuscript Palavras-chave: Chemistry; Pharmacology. Ano: 2009 URL: http://precedings.nature.com/documents/3676/version/2 Development and Characterization of Eudragit RS 100 Loaded Microsponges and its Colonic Delivery Using Natural Polysaccharides Nature Precedings Vikas Jain; Ranjit Singh. In the present work, paracetamol loaded eudragit based microsponges were prepared using quasi-emulsion solvent diffusion method. The compatibility of the drug with various formulation components was established. Process parameters were analyzed in order to optimize the formulation. Shape and surface morphology of the microsponges were examined using scanning electron microscopy. The colon specific formulations were prepared by compression coating of microsponges with pectin:hydroxypropylmethylcellulose (HPMC) mixture followed by tabletting. The in vitro dissolution studies were done on all formulations and the results were evaluated kinetically and statically. The kinetics of release study showed that the release data followed Higuchi matrix and the main... Tipo: Manuscript Palavras-chave: Chemistry; Pharmacology. Ano: 2009 URL: http://precedings.nature.com/documents/3676/version/1 Registros recuperados: 2 Primeira ... 1 ... Última

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