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Clinical and epidemiological characteristics associated with unfavorable tuberculosis treatment outcomes in TB-HIV co-infected patients in Brazil: a hierarchical polytomous analysis BJID
Prado,Thiago Nascimento do; Rajan,Jayant V.; Miranda,Angélica Espinosa; Dias,Elias dos Santos; Cosme,Lorrayne Beliqui; Possuelo,Lia Gonçalves; Sanchez,Mauro N.; Golub,Jonathan E.; Riley,Lee W.; Maciel,Ethel Leonor.
Abstract Background: TB patients co-infected with HIV have worse treatment outcomes than non-coinfected patients. How clinical characteristics of TB and socioeconomic characteristics influence these outcomes is poorly understood. Here, we use polytomous regression analysis to identify clinical and epidemiological characteristics associated with unfavorable treatment outcomes among TB-HIV co-infected patients in Brazil. Methods: TB-HIV cases reported in the Brazilian information system (SINAN) between January 1, 2001 and December 31, 2011 were identified and categorized by TB treatment outcome (cure, default, death, and development of MDR TB). We modeled treatment outcome as a function of clinical characteristics of TB and patient socioeconomic...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Tuberculosis; HIV; Coinfection; Logistic regression.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702017000200162
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blaGES carrying Pseudomonas aeruginosa isolates from a public hospital in Rio de Janeiro, Brazil BJID
Pellegrino,Flávia L. P. C.; Netto-dos Santos,Kátia R.; Riley,Lee W.; Moreira,Beatriz M..
Previous analysis of Pseudomonas aeruginosa class-1 integrons from Rio de Janeiro, Brazil, revealed the blaGES gene in one isolate. We screened isolates of two widespread PFGE genotypes, A and B, at a public hospital in Rio, for the presence of blaGES. The gene was detected in all seven P. aeruginosa isolates belonging to genotype B. Three of the seven genotype-B isolates were resistant to amikacin, aztreonam, ceftazidime, cefepime, ciprofloxacin, gentamicin, imipenem, meropenem, piperacillin-tazobactam and ticarcillin-clavulanic acid. The other four isolates were resistant to all these agents, except gentamicin, imipenem, meropenem and piperacillin-tazobactam. A synergistic effect between ceftazidime and imipenem or clavulanic acid suggested the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Pseudomonas aeruginosa blaGES; Antibiotics public hospital Rio de Janeiro Brazil.
Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702006000400007
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