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| Armesto, Paula; Campinho, Marco A.; Rodríguez-rúa, Ana; Cousin, Xavier; Power, Deborah M.; Manchado, Manuel; Infante, Carlos. |
| In the present work, five genes encoding different Na+,K+ ATPase (NKA) α-isoforms in the teleost Solea senegalensis are described for the first time. Sequence analysis of predicted polypeptides revealed a high degree of conservation across teleosts and mammals. Phylogenetic analysis clustered the five genes into three main clades: α1 (designated atp1a1a and atp1a1b), α2 (designated atp1a2) and α3 (designated atp1a3a and atp1a3b) isoforms. Transcriptional analysis in larvae showed distinct expression profiles during development. In juvenile tissues, the atp1a1a gene was highly expressed in osmoregulatory organs, atp1a2 in skeletal muscle, atp1a1b in brain and heart and atp1a3a and atp1a3b mainly in brain. Quantification of mRNA abundance after a salinity... |
| Tipo: Text |
Palavras-chave: Senegalese sole Na+; K+ ATPase atp1a1a atp1a1b atp1a2 atp1a3a atp1a3b osmoregulation. |
| Ano: 2014 |
URL: http://archimer.ifremer.fr/doc/00195/30640/29093.pdf |
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