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| Barreto-Bergter,Eliana; Pinto,Marcia R.; Rodrigues,Marcio L.. |
| Ceramide monohexosides (CMHs, cerebrosides) are glycosphingolipids composed of a hydrophobic ceramide linked to one sugar unit. In fungal cells, CMHs are very conserved molecules consisting of a ceramide moiety containing 9-methyl-4,8-sphingadienine in amidic linkage to 2-hydroxyoctadecanoic or 2-hydroxyhexadecanoic acids, and a carbohydrate portion consisting of one residue of glucose or galactose. 9-Methyl 4,8-sphingadienine-containing ceramides are usually glycosylated to form fungal cerebrosides, but the recent description of a ceramide dihexoside (CDH) presenting phytosphingosine in Magnaporthe grisea suggests the existence of alternative pathways of ceramide glycosylation in fungal cells. Along with their unique structural characteristics, fungal... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Glucosylceramide; Cerebrosides; Glycosphingolipids; Fungal pathogens; Antifungal therapy. |
| Ano: 2004 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652004000100007 |
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| Nosanchuk,Joshua D.; Nosanchuk,Murphy D.; Rodrigues,Marcio L.; Nimrichter,Leonardo; Carvalho,Antonio C. Campos de; Weiss,Louis M.; Spray,David C.; Tanowitz,Herbert B.. |
| Abstract A rich, collaborative program funded by the US NIH Fogarty program in 2004 has provided for a decade of remarkable opportunities for scientific advancement through the training of Brazilian undergraduate, graduate and postdoctoral students from the Federal University and Oswaldo Cruz Foundation systems at Albert Einstein College of Medicine. The focus of the program has been on the development of trainees in the broad field of Infectious Diseases, with a particular focus on diseases of importance to the Brazilian population. Talented trainees from various regions in Brazil came to Einstein to learn techniques and study fungal, parasitic and bacterial pathogens. In total, 43 trainees enthusiastically participated in the program. In addition to... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: International collaboration; Training grant; Microbial pathogenesis; Global health. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822015000400945 |
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