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The effects of acute administration of the hydroalcoholic extract of rosemary (Rosmarinus officinalis L.) (Lamiaceae) in animal models of memory BJPS
Zanella,Camila Angela; Treichel,Helen; Cansian,Rogério Luis; Roman,Silvane Souza.
Rosmarinus officinalis (Rosemary) demonstrates antioxidant, antidepressant, diuretic, antinociceptive and antiulcerogenic activities. The present study was designed to examine the effects of the hydroalcoholic extract of R. officinalis on the memory of male mice. The behavioral tasks employed were social recognition (SR), the Morris water maze (MWM) and an inhibitory avoidance task (IA). The treatment with 150 and 300 mg/kg of R. officinalis improved the acquisition phase of learning of a new social memory in the SR task because a decrease was observed in the duration of social investigation. In the Morris water maze, no significant effect was observed on spatial memory when the groups were compared for the time spent in the correct quadrant. In the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Rosmarinus officinalis/pharmacognosy; Rosmarinus officinalis/hydroalcoholic extract; Rosmarinus officinalis/experimental study; Short-term memory/experimental study; Long-term memory/experimental study; Spatial memory/experimental study.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502012000300005
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Tissue injuries of wistar rats treated with hydroalcoholic extract of Sonchus oleraceus L. BJPS
Prichoa,Franciele Carla; Roman,Silvane Souza; Manfredini,Vanusa.
The use of plant species is emerging as an important alternative in the treatment of injuries. Therefore, the extract of Sonchus oleraceus 10% was employed in the repair of skin lesions. A total of 36 male Wistar rats were subjected to a punch injury and divided into three groups: a negative control, receiving no treatment, a positive control, treated with Dersani, and the experimental group treated with the extract. The injury was assessed macroscopically and microscopically. Morphometric data was collected at the 3rd, 5th and 7th postoperative day, and the experimental group showed greater changes in shrinkage of the lesion compared to control groups. On the 3rd postoperative day, the injury in the experimental group showed less necrotic tissue, lower...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Sonchus oleraceus/pharmacognosy; Skin lesions/treatment; Skin lesions/experimental study; Wound healing/experimental study; Medicinal plants.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502011000300019
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