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	Provedor de dados BJMBR (2) Autor Romero,J.C. (2) Gomez,S.I (1) Reckelhoff,J.F. (1) Strick,D.M. (1) Palavra-chave Essential hypertension (1) Isoprostanes (1) Kidney (1) Meclofenamate (1) NG-nitro-L-arginine methyl ester (1) Nitric oxide (1) Peroxynitrites (1) Renal circulation (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2008 (1) 2000 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Role of nitric oxide and prostaglandin in the maintenance of cortical and renal medullary blood flow BJMBR Gomez,S.I; Strick,D.M.; Romero,J.C.. This study was undertaken in anesthetized dogs to evaluate the relative participation of prostaglandins (PGs) and nitric oxide (NO) in the maintenance of total renal blood flow (TRBF), and renal medullary blood flow (RMBF). It was hypothesized that the inhibition of NO should impair cortical and medullary circulation because of the synthesis of this compound in the endothelial cells of these two territories. In contrast, under normal conditions of perfusion pressure PG synthesis is confined to the renal medulla. Hence PG inhibition should predominantly impair the medullary circulation. The initial administration of 25 µM kg-1 min-1 NG-nitro-L-arginine methyl ester produced a significant 26% decrease in TRBF and a concomitant 34% fall in RMBF, while the... Tipo: Info:eu-repo/semantics/article Palavras-chave: Kidney; NG-nitro-L-arginine methyl ester; Meclofenamate; Renal circulation. Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008000200014 Oxidative stress may explain how hypertension is maintained by normal levels of angiotensin II BJMBR Romero,J.C.; Reckelhoff,J.F.. It is well known that essential hypertension evolves in most patients with "near normal" levels of plasma renin activity. However, these levels appear to be responsible for the high levels of arterial pressure because they are normalized by the administration of angiotensin II converting inhibitors or angiotensin receptor antagonist. In experimental animals, hypertension can be induced by the continuous intravenous infusion of small doses of angiotensin II that are not sufficient to evoke an immediate pressor response. However, this condition resembles the characteristics of essential hypertension because the high levels of blood pressure exist with normal plasma levels of angiotensin II. It is suggested that small amounts of angiotensin whose plasma... Tipo: Info:eu-repo/semantics/article Palavras-chave: Nitric oxide; Isoprostanes; Peroxynitrites; Essential hypertension. Ano: 2000 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000000600006 Registros recuperados: 2 Primeira ... 1 ... Última

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