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	Provedor de dados BJMBR (3) Autor Roselino,A.M.F. (3) Chiossi,M.P.V. (2) Costa,R.S. (1) Figueiredo,J.F.C. (1) Medeiros,A.C.R. (1) Rodrigues,S.S. (1) Zeoti,D.M. (1) Mais... Palavra-chave Fogo selvagem (2) Pemphigus foliaceus (2) Anti-CD1a (1) Bullous dermatoses (1) Cutaneous leishmaniasis (1) Cytokines (1) Dendritic cells (1) Histopathological detection (1) Langerhans cells (1) Leishmania detection (1) Leishmaniasis (1) PCR (1) Pemphigus (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Info:eu-repo/semantics/other (1) Ano 2004 (1) 2002 (1) 2000 (1) País Brazil (3) Idioma Inglês (3)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 3 Primeira ... 1 ... Última Serum cytokines in patients with Brazilian pemphigus foliaceus (fogo selvagem) BJMBR Zeoti,D.M.; Figueiredo,J.F.C.; Chiossi,M.P.V.; Roselino,A.M.F.. Pemphigus foliaceus (PF) is characterized by acantholysis determined by IgG4 binding to desmoglein I, a 160-kDa desmosomal glycoprotein. To investigate the immunopathological aspects of Brazilian PF, we determined levels of serum cytokines in patients with PF. Twenty-five patients with PF and a control group consisting of 10 healthy individuals were studied. Serum IL-2, IL-4, IL-5, IL-10, IL-12 and IFN-gamma were measured in the two groups by ELISA. The median concentration of IL-2 was lower in PF patients compared to the control group (0.45 and 9.50 pg/ml, respectively), as also was the concentration of IL-4 (0.26 and 10.16 pg/ml, respectively). The same was observed for IL-5 (7.94 and 15.74 pg/ml, respectively) and for IFN-gamma (5.90 and 8.58 pg/ml,... Tipo: Info:eu-repo/semantics/article Palavras-chave: Cytokines; Pemphigus; Pemphigus foliaceus; Fogo selvagem; Bullous dermatoses. Ano: 2000 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000000900012 Comparison of the specificity of PCR and the histopathological detection of leishmania for the diagnosis of American cutaneous leishmaniasis BJMBR Medeiros,A.C.R.; Rodrigues,S.S.; Roselino,A.M.F.. More precise and rapid diagnostic methods for American cutaneous leishmaniasis (ACL) are necessary because of the growing number of cases observed in Brazil, including the northeastern region of the State of São Paulo. We applied PCR to 54 skin or mucosal biopsies from patients with a clinical and/or laboratory diagnosis of ACL using primers 13A and 13B, with positive results being obtained for 82% of the samples. When the PCR results were compared to those of histopathological leishmania detection, PCR showed superior results with 81.5% sensitivity and 95% CI of 68.0-95.1%. The Montenegro skin test (MST) was positive in 88.7% of patients. Since MST cannot be used as a diagnostic tool in endemic areas, the present results strongly suggest the use of PCR... Tipo: Info:eu-repo/semantics/article Palavras-chave: Leishmaniasis; Cutaneous leishmaniasis; PCR; Histopathological detection; Leishmania detection. Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002000400002 Dermal dendritic cell number correlates with serum autoantibody titers in Brazilian pemphigus foliaceus patients BJMBR Chiossi,M.P.V.; Costa,R.S.; Roselino,A.M.F.. Pemphigus foliaceus (PF) is an autoimmune bullous disease endemic in Brazil. Since serum IL-12 is increased in patients with PF and Langerhans cells (LC) produce IL-12, we titrated serum autoantibodies by indirect immunofluorescence, and quantified epidermal dendritic cells, known as LC, and dermal dendritic cells (DC). Biopsies of blistering lesions were obtained from 22 patients, 13 of whom were submitted to biopsy of both injured and of apparently healthy skin. The control groups consisted of skin from 8 cadavers and from 12 women submitted to breast plastic surgery. LC and DC were identified with anti-CD1a antibody and quantified by morphometric analysis. LC number in the lesion and in apparently healthy skin from PF patients was similar to that of... Tipo: Info:eu-repo/semantics/other Palavras-chave: Anti-CD1a; Dendritic cells; Fogo selvagem; Langerhans cells; Pemphigus foliaceus. Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000300008 Registros recuperados: 3 Primeira ... 1 ... Última

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