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ABSENCE OF SEASONAL EFFECT ON THE IMMUNOMODULATORY ACTION OF BRAZILIAN PROPOLIS ON NATURAL KILLER ACTIVITY J. Venom. Anim. Toxins
SFORCIN,J. M.; KANENO,R.; FUNARI,S. R. C..
Propolis, a beehive product widely used in folk medicine as an antiinflammatory agent, has been attracting researchers' attention to scientifically elucidate its biological properties and therapeutic activities. The aim of this paper was to study the possible effect of propolis on natural killer activity, since propolis immunomodulatory action has been suggested, especially on non-specific immunity. Propolis was produced by africanized honeybees (Apis mellifera L.), collected throughout a whole year, and pooled by season. Hydroalcoholic solutions of propolis were prepared with each pool and administered to rats by gavage over three days. Natural killer activity of non-adherent spleen cells was evaluated by the 51Cr-release cytotoxicity assay against Yac-1...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Propolis; Season; Immunomodulation; Natural killer activity; Cytotoxic assay.
Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79302002000100003
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Seasonal effect of brazilian propolis on Candida albicans and Candida tropicalis J. Venom. Anim. Toxins
SFORCIN,J. M.; FERNANDES JÚNIOR,A.; LOPES,C. A. M.; FUNARI,S. R. C.; BANKOVA,V..
Recently, propolis has been attracting the attention of researchers due to various biological activities and therapeutic properties. In Brazil, propolis is produced all year long, so there may be some seasonal variations. This work was carried out in order to compare propolis collected during the four seasons by its in vitro antimicrobial activity on yeast pathogens isolated from human infections. Propolis was produced by africanized honeybees in Botucatu, São Paulo State, collected throughout a year and pooled by season. Hydroalcoholic solutions of propolis were prepared with each pool and diluted in agar, using serial concentrations of propolis from each pool. A determination of minimal inhibitory concentration (MIC) was performed. The results show that...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Propolis; Season; Candida; Antimicrobial activity.
Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79302001000100009
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POPULATION ANALYSIS OF SUSCEPTIBILITY TO PROPOLIS IN REFERENCE STRAINS OF Staphylococcus aureus AND Escherichia coli J. Venom. Anim. Toxins
FERNANDES Jr.,A.; LOPES,C. A. M.; SFORCIN,J. M.; FUNARI,S.R.C..
Susceptibility to several ethanolic extracts of propolis (EEP) concentrations was tested with the population analysis technique in reference strains of Staphylococcus aureus (ATCC 25923) and Escherichia coli (ATCC 35218). The results of these tests showed that all bacteria were killed by EEP concentrations approximately equal or higher (2.0% v/v- S. aureus; 10.0% v/v - E. coli) than the respective minimal inhibitory concentrations (MIC). Regarding the susceptibility to propolis, there was a homogeneity of data with the respective time kill curves showing a clear bactericidal effect during 6 to 9 h of exposition.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Propolis; Population analysis; Susceptibility; Staphylococcus aureus; Escherichia coli.
Ano: 1997 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79301997000200005
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Seasonal effect of Brazilian propolis on seric biochemical variables J. Venom. Anim. Toxins
SFORCIN,J. M.; NOVELLI,E. L. B.; FUNARI,S. R. C..
Propolis has been the subject of recent scientific investigation due to its biological properties, such as antibiotic, antiinflammatory, anesthetic, healing, immunomodulatory, antioxidant, and carcinostatic. The purpose of this study was to analyze the biochemical profile of propolis-treated rats to observe whether propolis might lead to side effects after administration. Evaluation of total protein, glucose, urea, creatinine, triglycerides, cholesterol, and HDL-cholesterol concentrations and determination of aminotransferases (AST and ALT) and lactic dehydrogenase (LDH) in propolis-treated rat serum were performed. The seasonal effect on propolis activity was also analyzed, considering the biochemical variables evaluated. The lack of clinically important...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Propolis; Season; Biochemistry; Serum.
Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79302002000200005
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