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Evaluation of Placental Epigenetic Changes due to Morphine Consumption International Journal of Morphology
Kazemi,Masoomeh; Tekieh,Elaheh; Golabi,Sahar; Sahraei,Hedayat.
Based on previous studies, a variety of bioenvironmental elements including inappropriate nutrition, diseases, infections, stressors, and medications are involved in epigenetic changes. Drug abuse is one of the most important causes of epigenetic changes and a concern in today's world. Studies have shown that morphine use by pregnant mothers causes several disorders in mothers in addition to transferring abnormalities to the next generation (placenta and embryo). Epigenetic factors such as morphine cause changes in gene expression in placenta as the first embryonic defense barrier. Because placenta does all the nutritional exchanges between mother's and embryo's blood, placental health guarantees normal embryonic development. Many studies have been...
Tipo: Journal article Palavras-chave: Development; Morphine; Embryo; Epigenetic; Pregnancy; Placenta.
Ano: 2016 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022016000100036
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Effect of Intermittent Feeding on Gonadal Function in Male And Female NMRI Mice During Chronic Stress BABT
Ehteram,Badri Zarrin; Sahraei,Hedayat; Meftahi,Gholam Hossein; Khosravi,Maryam.
ABSTRACT Stress can inhibit gonadal activity via Hypothalamus-Pituitary-Gonad (HPG) axis activity suppression. In the present study, effects of intermittent feeding (IF) on gonadal function under stress in male and female mice were evaluated. Twenty eight male and twenty eight female mice's were divided into four groups. The control group received adequate food and water without stress. The second group received four days of electric shock without food deprivation. The third group was deprived of food two hours/day for a week, and the fourth group was deprived of food (2 hours/day for seven consecutive days) and then electric foot shock stress was applied to them for four days. Blood samples were collected from all animals for plasma testosterone, estrogen...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Estrogen; Gonad; IL-6; Intermittent Feeding; Stress; Testosterone.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132017000100439
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