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| Oliveira Filho,Claudio Costa; Kampke,Edgar Hell; Vargas,Thais Souza; Salustriano,Nathacha Andrade; Scherer,Rodrigo; Fronza,Marcio; Campagnaro,Bianca Prandi. |
| ABSTRACT The objective was to investigate the total saponin and protodioscin concentrations and the cytotoxicity in vitro, of five samples of the plant Tribulus terrestris, commercially available in the metropolitan region of Vitória - Espirito Santo, Brazil, and to compare them with the aqueous extract of the plant. The chromatographic profile and quantification of protodioscin in commercial samples and plant extract were evaluated by LC-MS/MS. The percentage of total saponins were determined by the colorimetric method. Extracts and protodioscin cytotoxicity were analyzed by the MTT assay in three cell lineages: fibroblasts (L929), ovarian cancer (Ovcar3) and murine hepatoma (Hepa1c1c7). All extracts displayed high levels of total saponins (207.2 to 780.3... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Tribulus terrestres/saponin/protodioscin/concentrations; Medicinal plants; Cytotoxicity/in vitro. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502017000400622 |
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