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Distinct strains of Staphylococcus aureus lead to different inflammatory response patterns in a murine model of intradermal infection Biological Sciences
Santana, Hugo; Ferreira, Lício Fábio Almeida Andrade; Pereira, Ítalo Sousa; Marques, Lucas Miranda; Fiqueiredo, Tiana Baqueiro; Silva, Robson Amaro Augusto da.
Staphylococcus aureus infection may lead to the development of soft tissue damage. It has been evaluated in other researches using different animal models. In addition, the inflammatory response developed by the host organism facing an infection by this pathogen has been analyzed and neutrophils have been linked to the immune response developed. In this study, we aimed to compare the inflammatory response developed by the host induced by an intradermal infection with a methicillin-resistant strain of Staphylococcus aureus (MRSA) or a methicillin-susceptible strain of Staphylococcus aureus (MSSA). Mice euthanasia occurred in the following times: 6, 24, 48 and 96 hours of infection; the cell number and the cytokine release were evaluated. Our results showed...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Ciências Biológicas Neutrophil; Lymph node; MRSA Microbiologia.
Ano: 2016 URL: http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/30572
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