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	Provedor de dados BJMBR (2) Autor Santos,J.C. (2) Coviello,A. (1) Jerez,S. (1) Ladeira,M.S.P. (1) Pedrazzoli Jr,J. (1) Peral de Bruno,M. (1) Ribeiro,M.L. (1) Mais... Palavra-chave Angiotensin-(1-7) (1) Chronic gastritis (1) Gastric cancer (1) Helicobacter pylori (1) IL-1RN (1) IL-1β (1) Interleukins (1) Osmotic water permeability (1) Polymorphisms (1) Receptor subtypes (1) TNF-α (1) Toad skin (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2012 (1) 2000 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Relationship of IL-1 and TNF-α polymorphisms with Helicobacter pylori in gastric diseases in a Brazilian population BJMBR Santos,J.C.; Ladeira,M.S.P.; Pedrazzoli Jr,J.; Ribeiro,M.L.. It is well known that the risk of development of gastric cancer (GC) in Helicobacter pylori-infected patients depends on several factors. Thus, the aim of this study was to investigate the effect of proinflammatory cytokine gene polymorphisms for IL-1β, IL-1RN and TNF-α on the development of GC in a Brazilian population. A total of 202 biopsies obtained from Brazilian patients with chronic gastritis and GC were included in the study. Infection with H. pylori cagA+ was determined by the polymerase chain reaction (PCR) as previously described. IL-1β, IL-1RN and TNF-α polymorphism genotyping was performed by restriction fragment length polymorphism PCR. Associations between gene polymorphisms, clinical diseases and virulence markers were evaluated using... Tipo: Info:eu-repo/semantics/article Palavras-chave: Chronic gastritis; Gastric cancer; Polymorphisms; Helicobacter pylori; Interleukins; IL-1β; IL-1RN; TNF-α. Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000900004 Angiotensin-(1-7) increases osmotic water permeability in isolated toad skin BJMBR Santos,J.C.; Jerez,S.; Peral de Bruno,M.; Coviello,A.. Angiotensin-(1-7) (Ang-(1-7)) increased osmotic water permeability in the isolated toad skin, a tissue with functional properties similar to those of the distal mammalian nephron. Concentrations of 0.1 to 10 µM were effective, with a peak at 20 min. This effect was similar in magnitude to that of frog skin angiotensin II (Ang II) and oxytocin but lower than that of human Ang II and arginine-vasotocin. The AT2 angiotensin receptor antagonist PD 123319 (1.0 µM) fully inhibited the response to 0.1 µM Ang-(1-7) but had no effect on the response to Ang II at the same concentration. The specific receptor antagonist of Ang-(1-7), A-779, was ineffective in blocking the response to Ang-(1-7) and to frog skin Ang II. The AT1 receptor subtype antagonist losartan,... Tipo: Info:eu-repo/semantics/article Palavras-chave: Angiotensin-(1-7); Toad skin; Osmotic water permeability; Receptor subtypes. Ano: 2000 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000000900018 Registros recuperados: 2 Primeira ... 1 ... Última

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