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Hydroxyapatite-lignin composite as a metallic implant-bone tissue osseointegration improver: experimental study in dogs Ciência Rural
Valente,Fabrício Luciani; Santos,Letícia Corrêa; Sepúlveda,Rodrigo Viana; Gonçalves,Gustavo Pereira; Eleotério,Renato Barros; Reis,Emily Correna Carlo; Borges,Andréa Pacheco Batista.
The study aimed to evaluate biocompatibility, osteoconduction and osseointegration of a pasty composite of hydroxyapatite (20%) and lignin (80%) as a promoter of metal implant and bone tissue integration. An intramedullary Schanz pin was implanted in both tibias of fifteen bitches. In the left tibia, the pin was coated with the biomaterial at the time of surgery. Marrow cavity was also filled with the biomaterial. Right limb did not receive the biomaterial, then constituting the control group. Tibias were harvested from five animals at 8, 60 and 150 days after surgery; three of them were analyzed by histological and biomechanical assessment and the two remaining tibias by X-ray diffraction. Results showed that the biomaterial is biocompatible, with...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Biomaterial; Biocompatibility; Osseointegration; Osteoconduction; Tissue regeneration.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782016000200324
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