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	Provedor de dados BJMBR (1) Autor Moura,E.G. (1) Pazos-Moura,C.C. (1) Santos,C.V.M. (1) Santos,R.M.M. (1) Palavra-chave Gastrin-releasing peptide (1) Substance P (1) Thyrotropin (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 1999 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Interaction between substance P and gastrin-releasing peptide on thyrotropin secretion by rat pituitary in vitro BJMBR Moura,E.G.; Santos,C.V.M.; Santos,R.M.M.; Pazos-Moura,C.C.. The effect of substance P (SP) on thyrotropin (TSH) secretion is controversial. In this study we evaluated the effect of SP on TSH secretion by hemipituitaries of 3-month-old Wistar rats in vitro and its interaction with gastrin-releasing peptide (GRP) at equimolar concentrations (1 µM and 10 µM). TSH release was measured under basal conditions and 30 min after incubation in the absence or presence of SP, GRP or both peptides. Pituitary TSH content was also measured in the pituitary homogenate after incubation. SP at both concentrations caused a significant (P<0.05) increase in TSH secretion compared with all other groups, which was approximately 60% (1 µM) and 85% (10 µM) higher than that of the control group (23.3 ± 3.0 ng/ml). GRP at the lower... Tipo: Info:eu-repo/semantics/article Palavras-chave: Substance P; Thyrotropin; Gastrin-releasing peptide. Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000900015 Registros recuperados: 1 Primeira ... 1 ... Última

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