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HD genotype imputation in 54k genotype and ungenotyped Original Braunvieh and Brown Swiss cattle Organic Eprints
Gredler, B.; Sargolzaei, M.; Bapst, B.; Bieber, A.; Simianer, H.; Seefried, F..
In silico genotyping by imputation of unknown genotypes can be used to reduce the implementation costs of genomic selection. We evaluated the accuracy of genotype imputation from Illumina 54k to High Density (HD) in Orginial Braunvieh and Brown Swiss cattle in Switzerland.
Tipo: Conference paper, poster, etc. Palavras-chave: Dairy cattle; Breeding and genetics.
Ano: 2013 URL: http://orgprints.org/36414/1/gredler-etal-2013-Nantes_2013_presentation.pdf
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Accuracy of 54K to HD gebotype imputation in Brown Swiss cattle Organic Eprints
Gredler, B.; Sargolzaei, M.; Bapst, B.; Bieber, A.; Simianer, H.; Seefried, F.R..
Imputation of genotypes can be used to reduce the implementation costs of genomic selection. In this study, we evaluated the accuracy of genotype imputation from Illumina 54k to Illumina High Density (HD) in Brown Swiss cattle. Genotype data comprised 6,106 54k and 880 HD genotyped bulls and cows of Brown Swiss and Original Braunvieh cattle. Genotype data was checked for parentage conflicts and SNP were excluded if MAF was below 0.5% and SNP call rate was lower than 90%. The final data set included 39,004 SNP for the 54k and 627,306 SNP for the HD chip. HD genotypes of animals born between 2004 and 2008 (n=365) were masked to mimic animals genotyped with the 54k chip. Methods used for imputation were FImpute and Findhap V2. Both programs use pedigree...
Tipo: Conference paper, poster, etc. Palavras-chave: Breeding and genetics.
Ano: 2013 URL: http://orgprints.org/36412/1/Gredler-etal-2013_Plant_Animal_Genome_XXI_Congress_SanDiego_USA.pdf
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