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Carvalho, Raquel N.; Arukwe, Augustine; Ait-aissa, Selim; Bado-nilles, Anne; Balzamo, Stefania; Baun, Anders; Belkin, Shimshon; Blaha, Ludek; Brion, Francois; Conti, Daniela; Creusot, Nicolas; Essig, Yona; Ferrero, Valentina E. V.; Flander-putrle, Vesna; Furhacker, Maria; Grillari-voglauer, Regina; Hogstrand, Christer; Jonas, Adam; Kharlyngdoh, Joubert B.; Loos, Robert; Lundebye, Anne-katrine; Modig, Carina; Olsson, Per-erik; Pillai, Smitha; Polak, Natasa; Potalivo, Monica; Sanchez, Wilfried; Schifferli, Andrea; Schirmer, Kristin; Sforzini, Susanna; Sturzenbaum, Stephen R.; Softeland, Liv; Turk, Valentina; Viarengo, Aldo; Werner, Inge; Yagur-kroll, Sharon; Zounkova, Radka; Lettieri, Teresa. |
The risk posed by complex chemical mixtures in the environment to wildlife and humans is increasingly debated, but has been rarely tested under environmentally relevant scenarios. To address this issue, two mixtures of 14 or 19 substances of concern (pesticides, pharmaceuticals, heavy metals, polyaromatic hydrocarbons, a surfactant, and a plasticizer), each present at its safety limit concentration imposed by the European legislation, were prepared and tested for their toxic effects. The effects of the mixtures were assessed in 35 bioassays, based on 11 organisms representing different trophic levels. A consortium of 16 laboratories was involved in performing the bioassays. The mixtures elicited quantifiable toxic effects on some of the test systems... |
Tipo: Text |
Palavras-chave: Bioassays; Effects; Mixtures; Ecotoxicology; Biomarkers. |
Ano: 2014 |
URL: https://archimer.ifremer.fr/doc/00499/61115/64667.pdf |
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Banni, Mohamed; Sforzini, Susanna; Arlt, Volker M.; Barranger, Audrey; Dallas, Lorna J.; Oliveri, Caterina; Aminot, Yann; Pacchioni, Beniamina; Millino, Caterina; Lanfranchi, Gerolamo; Readman, James W.; Moore, Michael N.; Viarengo, Aldo; Jha, Awadhesh N.. |
Despite the increasing use of mussels in environmental monitoring and ecotoxicological studies, their genomes and gene functions have not been thoroughly explored. Several cDNA microarrays were recently proposed for Mytilus spp., but putatively identified partial transcripts have rendered the generation of robust transcriptional responses difficult in terms of pathway identification. We developed a new low density oligonucleotide microarray with 465 probes covering the same number of genes. Target genes were selected to cover most of the well-known biological processes in the stress response documented over the last decade in bivalve species at the cellular and tissue levels. Our new 'STressREsponse Microarray' (STREM) platform consists of eight sub-arrays... |
Tipo: Text |
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Ano: 2017 |
URL: https://archimer.ifremer.fr/doc/00476/58751/61280.pdf |
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