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	Provedor de dados 55 (1) 60 (1) Autor Shen,Li (2) Chen,Jianguo (1) Chen,Zhonghua (1) Jiang,Jinghui (1) Liu,Xing (1) Mao,Lingxiang (1) Wu,Jing (1) Xu,Huaxi (1) Yang,Changyong (1) Mais... Palavra-chave 1H NMR (1) Acute pancreatitis/analysis (1) Enterovirus (1) Infection (1) Metabolomics (1) MicroRNAs (1) Pathological changes (1) Rats (1) Rheum/effects (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2017 (1) 2015 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última The role of microRNAs in enteroviral infections 55 Wu,Jing; Shen,Li; Chen,Jianguo; Xu,Huaxi; Mao,Lingxiang. ABSTRACTThe genus Enterovirus, a member of thePicornavirus family, are RNA viruses that can cause poliomyelitis, hand-food-mouth disease, viral meningitis or meningoencephalitis, viral myocarditis and so on. MicroRNAs are a class of highly conserved, small noncoding RNAs recognized as important regulators of gene expression. Recent studies found that MicroRNAs play a significant role in the infection ofEnterovirus, such as enterovirus 71, coxsackievirus B3 and other Enterovirus. Enteroviral infection can alter the expression of cellular MicroRNAs, and cellular MicroRNAs can modulate viral pathogenesis and replication by regulating the expression level of viral or host's genes. Herein, this review summarizes the role of MicroRNAs in enteroviral infection. Tipo: Info:eu-repo/semantics/article Palavras-chave: MicroRNAs; Enterovirus; Infection. Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702015000500510 Metabolic analysis of the effect of rheum on a taurocholate-induced acute pancreatitis rat model 60 Chen,Zhonghua; Shen,Li; Yang,Changyong; Jiang,Jinghui; Liu,Xing. ABSTRACT The effects of rheum on serum parameters in a taurocholate-induced acute pancreatitis (AP) rat model were investigated using pathological and biochemical tests, and a proton nuclear magnetic resonance (1H NMR)-based metabonomic strategy. Healthy rats and rats with AP were either treated with rheum (7.5% at a dose of 1.5 g/kg) or left untreated. Serum samples were collected from the AP and rheum-treated groups at 6, 12, and 24 h after treatment. The effect of rheum on pathological changes in the pancreatic was investigated to validate the AP model. We obtained 1H NMR spectra and analyzed the results using the partial least squares discriminant method. The results of the pathological and metabolic analyses revealed an amelioration of multiple... Tipo: Info:eu-repo/semantics/article Palavras-chave: Rheum/effects; Acute pancreatitis/analysis; Metabolomics; 1H NMR; Pathological changes; Rats. Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502017000200633 Registros recuperados: 2 Primeira ... 1 ... Última

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