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CHANGE OF THE MTOR PATHWAY IN TISSUES OF OVERFED GEESE Rev. Bras. Ciênc. Avic.
Han,C; Ye,F; Shen,X; Liu,D; He,F; Wei,S; Xu,H; Li,L; Liu,H.
ABSTRACTThis study aimed at examining the effect of overfeeding on the activity of the mTOR pathway in the liver and muscle tissues of Gang geese. Eighty healthy male Gang geese were reared under the same feeding conditions, and were divided at 14 weeks of age into a control group and an overfed group. All birds were slaughtered after three weeks of over feeding. Gene expression and protein content of several genes involved in the mTOR pathway were evaluated. The results showed that the gene expression of mTOR, raptor, and rictor, and the protein contents of mTOR and PI3K were higher in liver, breast muscle, and leg muscle of the overfed group than that of control group. However, the S6K expression level was clearly lower in the liver of the overfed group...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Goose; MTOR pathway; Overfeeding; Tissues.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-635X2015000300293
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Detection of Snps in the Melanocortin 1-Receptor (MC1R) and Its Association with Shank Color Trait in Hs Chicken Rev. Bras. Ciênc. Avic.
Shen,X; Wang,Y; Cui,C; Zhao,X; Li,D; Zhu,Q; Jiang,X; Yang,C; Qiu,M; Yu,C; Li,Q; Du,H; Zhang,Z; Yin,H.
ABSTRACT The melanocortin 1 receptor (MC1R) gene plays a key role in controlling the deposition of melanin. In mammals, the MC1Rgene is regarded as a major candidate gene in the control of melanin formation. In domestic animals, the MC1R gene mainly controls the expression of coat, skin, and plumage color in mammals and birds. In order to breed chickens with dark-green shank faster, we screened the molecular markers for shank color in a HS chicken population by exploring the relationship between polymorphism of the MC1R gene and three different shank colors (light green, dark green and yellow). Two primer pairs for code region of the MC1R gene were designed in the basic of chicken genomic sequence. DNA sequencing was performed to detect the polymorphisms...
Tipo: Info:eu-repo/semantics/article Palavras-chave: HS chicken; MC1R gene; Polymorphisms; Shank color..
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-635X2019000300314
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