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	Provedor de dados BJMBR (4) Autor Shi,H.M. (4) Jin,B. (3) Wen,Z.C. (3) Wu,B.W. (3) Luo,X.P. (2) Zhu,J. (2) Chan,L.W. (1) Gu,X.Y. (1) Li,J. (1) Liu,L. (1) Ni,H.C. (1) Qiao,J. (1) Zhang,J.J. (1) Mais... Palavra-chave Meta-analysis (2) Polymorphism (2) CD62p (1) Contrast-induced nephropathy Reduced glutathione Randomized (1) Controlled trial (1) Coronary heart disease (1) Dilated cardiomyopathy (1) HLA-DR (1) High-density lipoprotein cholesterol (1) Low-density lipoprotein cholesterol (1) PAC-1 (1) Platelet activation (1) Statins (1) Toll-like receptor 4 (1) Mais... Tipo do documento Info:eu-repo/semantics/article (4) Ano 2017 (1) 2016 (1) 2015 (2) País Brazil (4) Idioma Inglês (4)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 4 Primeira ... 1 ... Última Association between Toll-like receptor 4 Asp299Gly polymorphism and coronary heart disease susceptibility BJMBR Wu,B.W.; Zhu,J.; Shi,H.M.; Jin,B.; Wen,Z.C.. Published data on the association between Toll-like receptor 4 (TLR4) Asp299Gly polymorphism and coronary heart disease (CHD) susceptibility are inconclusive. To derive a more precise estimation of the relationship, a meta-analysis was performed. English-language studies were identified by searching PubMed and Embase databases (up to November 2016). All epidemiological studies were regarding Caucasians because no TLR4 Asp/Gly and Gly/Gly genotypes have been detected in Asians. A total of 20 case-control studies involving 14,416 cases and 10,764 controls were included in the meta-analysis. Overall, no significant associations were found between TLR4 Asp299Gly polymorphism and CHD susceptibility in the dominant model (OR=0.89; 95%CI=0.74 to 1.06; P=0.20)... Tipo: Info:eu-repo/semantics/article Palavras-chave: Toll-like receptor 4; Polymorphism; Coronary heart disease; Meta-analysis. Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2017000900609 Preventive effect of reduced glutathione on contrast-induced nephropathy in elderly patients undergoing coronary angiography or intervention: a randomized, controlled trial BJMBR Jin,B.; Wu,B.W.; Zhang,J.J.; Luo,X.P.; Shi,H.M.. Coronary angiography can be a high-risk condition for the incidence of contrast-induced nephropathy (CIN) in elderly patients. Reduced glutathione, under a variety of mechanisms, may prevent CIN in this procedure. We prospectively examined whether hydration with reduced glutathione is superior to hydration alone for prevention of CIN in an elderly Han Chinese population. A total of 505 patients (271 males and 234 females) aged 75 years or older who underwent non-emergency coronary angiography or an intervention were randomly divided into two groups. The treatment group received hydration with reduced glutathione (n=262) and the control group received hydration alone (n=243). Serum creatinine and blood urea nitrogen levels were measured prior to coronary... Tipo: Info:eu-repo/semantics/article Palavras-chave: Contrast-induced nephropathy Reduced glutathione Randomized; Controlled trial. Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2015000900839 HLA-DR3 antigen in the resistance to idiopathic dilated cardiomyopathy BJMBR Jin,B.; Wu,B.W.; Wen,Z.C.; Shi,H.M.; Zhu,J.. Idiopathic dilated cardiomyopathy (IDC) has been hypothesized as a multifactorial disorder initiated by an environment trigger in individuals with predisposing human leukocyte antigen (HLA) alleles. Published data on the association between HLA-DR3 antigen and IDC risk are inconclusive. To derive a more precise estimation of the relationship, a meta-analysis was performed. Studies were identified by searching the PUBMED and Embase database (starting from June 2015). A total of 19 case-control studies including 1378 cases and 10383 controls provided data on the association between HLA-DR3 antigen and genetic susceptibility to IDC. Overall, significantly decreased frequency of HLA-DR3 allele (OR=0.72; 95%CI=0.58-0.90; P=0.004) was found in patients with IDC... Tipo: Info:eu-repo/semantics/article Palavras-chave: HLA-DR; Dilated cardiomyopathy; Polymorphism; Meta-analysis. Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000400708 High levels of LDL-C combined with low levels of HDL-C further increase platelet activation in hypercholesterolemic patients BJMBR Chan,L.W.; Luo,X.P.; Ni,H.C.; Shi,H.M.; Liu,L.; Wen,Z.C.; Gu,X.Y.; Qiao,J.; Li,J.. High levels of low-density lipoprotein cholesterol (LDL-C) enhance platelet activation, whereas high levels of high-density lipoprotein cholesterol (HDL-C) exert a cardioprotective effect. However, the effects on platelet activation of high levels of LDL-C combined with low levels of HDL-C (HLC) have not yet been reported. We aimed to evaluate the platelet activation marker of HLC patients and investigate the antiplatelet effect of atorvastatin on this population. Forty-eight patients with high levels of LDL-C were enrolled. Among these, 23 had HLC and the other 25 had high levels of LDL-C combined with normal levels of HDL-C (HNC). A total of 35 normocholesterolemic (NOMC) volunteers were included as controls. Whole blood flow cytometry and platelet... Tipo: Info:eu-repo/semantics/article Palavras-chave: Low-density lipoprotein cholesterol; High-density lipoprotein cholesterol; Platelet activation; Statins; PAC-1; CD62p. Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2015000200167 Registros recuperados: 4 Primeira ... 1 ... Última

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