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| Dalben Dota,Kelen Fátima; Shinobu,Cristiane Suemi; Patussi,Eliana Valéria; Lopes Consolaro,Marcia Edilaine; Estivalet Svidzinski,Terezinha Inez. |
| Se determinó la susceptibilidad antifúngica in vitro de 78 cepas de levaduras aisladas de mujeres de la ciudad de Maringá/Paraná, Brasil, con candidiasis vulvovaginal (CVV), atendidas en el Laboratorio de Enseñanza e Investigación en Análisis Clínicos (LEPAC) de la Universidad Estatal de Maringá, desde el 1 de enero 2005 al 31 de diciembre 2006. Su sensibilidad in vitro fue investigada por el método de microdilución frente a ketoconazol (KETO), fluconazol (FLU), itraconazol (ITRA), nistatina (NIS) y anfotericina B (AMB). Para KETO, 41,5% de las cepas de C. albicans y 96% de Candida no-albicans presentaron resistencia (100% de C. glabrata) y para FLU solamente el 3,8% de los aislamientos de C. albicans y el 8,0% de C. glabrata fueron resistentes. Sólo 1,9%... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Candidiasis vulvovaginal; Tratamiento; Antifúngicos; Resistencia in vitro. |
| Ano: 2008 |
URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0325-29572008000400008 |
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| Shinobu,Cristiane Suemi; Ogatta,Sueli Fumie Yamada; Bizerra,Fenando; Furlaneto,Luciana; Peralta,Rosane Marina; Svidzinski,Terezinha Inez Estivalet; Consolaro,Marcia Edilaine Lopes. |
| The physiopathogenesis of vulvovaginal candidiasis (VVC) is still not completely elucidated. The objective of this study was to evaluate if there is a relationship between the different genotypes of Candida albicans, their main agent and the virulence of this yeast in vaginal isolates, and to check if there are laboratorial markers that can predict the ability of each isolate to develop VVC independently of symptoms. The production of exoenzymes protease, phospholipase and haemolysin, resistance to hydrogen peroxide, and the genotype were determined. Genotype A was predominant (75%), protease, phospholipase and haemolytic activity were highly expressed, and the majority of the yeasts were sensitive to H2O2 in 1 and 2 hours of exposure, suggesting that... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: C. albicans; Vulvovaginal candidiasis; Genotype; Virulence factors. |
| Ano: 2007 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822007000300015 |
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