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| Ameer,O.Z.; Salman,I.M.; Siddiqui,M.J.A.; Yam,M.F.; Sriramaneni,R.N.; Sadikun,A.; Ismail,Z.; Shah,A.M.; Asmawi,M.Z.. |
| We investigated the vascular responses and the blood pressure reducing effects of different fractions obtained from the methanol extract of Loranthus ferrugineus Roxb. (F. Loranthaceae). By means of solvent-solvent extraction, L. ferrugineus methanol extract (LFME) was successively fractionated with chloroform, ethyl acetate and n-butanol. The ability of these LFME fractions to relax vascular smooth muscle against phenylephrine (PE)- and KCl-induced contractions in isolated rat aortic rings was determined. In another set of experiments, LFME fractions were tested for blood pressure lowering activity in anesthetized adult male Sprague-Dawley rats (250-300 g, 14-18 weeks). The n-butanol fraction of LFME (NBF-LFME) produced a significant... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Loranthus ferrugineus; N-butanol fraction; Cardiovascular effect; Aortic ring; Vasorelaxation; Terpenoid. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010000200009 |
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