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| Veronese,F.V.; Dode,R.S.O.; Friderichs,M.; Thomé,G.G.; Silva,D.R. da; Schaefer,P.G.; Sebben,V.C.; Nicolella,A.R.; Barros,E.J.G.. |
| Levamisole has been increasingly used as an adulterant of cocaine in recent years, emerging as a public health challenge worldwide. Levamisole-associated toxicity manifests clinically as a systemic vasculitis, consisting of cutaneous, hematological, and renal lesions, among others. Purpura retiform, cutaneous necrosis, intravascular thrombosis, neutropenia, and less commonly crescentic nephritis have been described in association with anti-neutrophil cytoplasmic antibodies (ANCAs) and other autoantibodies. Here we report the case of a 49-year-old male who was a chronic cocaine user, and who presented spontaneous weight loss, arthralgia, and 3 weeks before admission purpuric skin lesions in the earlobes and in the anterior thighs. His laboratory tests on... |
| Tipo: Info:eu-repo/semantics/report |
Palavras-chave: Cocaine; Levamisole; Systemic vasculitis; ANCA; Retiform purpura; Crescentic glomerulonephritis. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000500501 |
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